Acharonim
Under Ottoman rule that had transformed Constantinople into Istanbul, the Jewish community flourished as one of the Mediterranean's most vibrant diaspora centers, swollen by Sephardi refugees fleeing Spain and Portugal after 1492. By the sixteenth and seventeenth centuries, the city housed perhaps twenty thousand Jews—merchants, physicians, craftsmen, and scholars distributed across crowded quarters in Balat and Galata, their synagogues reflecting the linguistic and ritual diversity of Greek, Spanish, Italian, and Ashkenazi traditions. The intellectual atmosphere crackled with Kabbalistic learning imported from Tzfat, while biblical commentary and halakhic innovation flourished in the yeshivas; R. Yaakov Culi's vast Me'am Loez project—an ambitious vernacular encyclopedia of Torah commentary—epitomized the era's drive to make sacred learning accessible to ordinary Jews across the Ottoman lands. The Grand Bazaar's silk and spice merchants were as likely to be Jewish as Muslim, and the Pasha's court occasionally sought Jewish physicians and administrators for counsel. Yet this prosperity existed precariously: the community's fortunes rose and fell with Ottoman state power and periodic blood libel accusations, and by the eighteenth century new religious movements rippled through even this cosmopolitan center.